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Canine Dose is calculated using Body Surface Area,(Automatically Converted Here) mcg/m2. Feline Dose is calculated using body weight, mcg/kg. Body Surface Area dosing may be a consideration for cats of smaller body weight. Accurate dosing is not possible with dogs weighing less than 2 kg.
125-500 mcg/m2 IM,IV
Feline
| lb | kg | Mild | Moderate | Deep |
|---|---|---|---|---|
| 4-7 | 2-3 | 0.025 ml | 0.05 ml | 0.1 – 0.15 ml |
| 7-9 | 3-4 | 0.05 ml | 0.1 ml | 0.2 – 0.25 ml |
| 9-13 | 4-6 | 0.1 ml | 0.2 ml | 0.3 – 0.35 ml |
| 14-15 | 6-7 | 0.2 ml | 0.3 ml | 0.4 – 0.45 ml |
| 15-18 | 7-8 | 0.3 ml | 0.4 ml | 0.5 – 0.55 ml |
20-30 mg/kg PO
Dogs,PO (0.5-5mg, depending on size)
About Chill Protocol Close
| Drug - Dose | Administration | Contraindications |
|---|---|---|
|
Gabapentin 20-30 mg/kg |
Give PO the night before, repeat dose 1-2 hrs prior to exam | Liver failure, Critically ill, Pediatrics |
| Melatonin Small dogs, 0.5-1mg PO; Medium dogs, 1-3mg PO; Large dogs, 5mg PO |
Give 1-2 hrs prior to exam, same time as Gabapentin | None |
| Acepromazine
Injectable(OTM) 0.025-0.05 mg/kg |
Give 30 min before exam | -Significant Cardiovascular, Kidney, Liver disease, Trauma, or Geriatric |
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Preanesthetics can reduce dose by 20-50%
Canine Dosages
| Preanesthetic | ALFAXAN® induction dose range |
| No preanesthetic | 2.2 (1.5 - 4.5)mg/kg |
| Benzodiazepine + opioid + phenothiazine | 2.3 (1.2-5.0)mg/kg |
| Opioid + acepromazine | 1.6 (0.6 - 3.5)mg/kg |
| Alpha2-agonist | 1.1 (0.21 - 2.00)mg/kg |
Feline Dosages
| Preanesthetic | ALFAXAN® induction dose range |
| No preanesthetic | 4.0 (2.2-9.7)mg/kg |
| Opioid + phenothiazine | 3.2 (1.1-10.8)mg/kg |
| Benzodiazepine + phenothiazine | 3.6 (1.5 – 7.1)mg/kg |
| Benzodiazepine + opioid + phenothiazine | 2.3 (1.2-5.0)mg/kg |
| Alpha2-adrenergic agonist with/without phenothiazine | 3.6 (1.1-5.0)mg/kg |
| Alpha2-adrenergic agonist + phenothiazine with/without benzodiazepine or opioid | 2.9 (1.0-3.9)mg/kg |
TTDex = Combine 2.5 ml Dexmedetomidine (500 mcg/ml) and 2.5 ml Butorphanol (10 mg/ml) with 1 bottle (500 mg) of Telazol powder.
Important Facts when using TTDex 1) Rapid drug onset occurs within 3-8 minutes after a single IM administration. 2) Always provide supplemental oxygen (via facemask or ETT). 3) About 75% of dogs and cats can be intubated with dosages of 0.02 ml/kg IM or greater. 4) TTDex may cause respiratory depression; anesthetist should ventilate patient when this occurs (apnea usually subsides with surgical manipulation). 5) If surgery will be longer than 30 minutes, the patient should be placed on isoflurane supplementation PRN (lower concentration at start (0.25%) and slowly increase isoflurane concentration to 1.5% by 45 minutes). 6) The dexmedetomidine within the TTDex can be reversed with Antisedan (give 1/2 volume of the TTDex dose IM). In dogs, wait atleast one hour before reversing (to prevent dissociative ‘hangover’. Cats may be reversed at anytime. 7) If stronger analgesia is needed, buprenorphine, hydromorphone or morphine may be given 30 minutes (or later) after TTDex administration. (Butorphanol concentration will be decreased and will have minimal impact (antagonism) on subsequent opioid administration). 8) Store the TTDex at room temperature (59-86F) for up to 3 months. DO NOT store this mixture in the refrigerator. 9) Sudden awakening may occur if painful procedures continue after 30 minutes of TTDex administration. Pre-emptive actions should be taken by administering opioids, or adjusting % of inhalant. 10) For a rough recovery (either due to delirium or pain) use a micro-dose of dexmedetomidine (to induce immediate sedation).
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