September 2010
NIOSH Publication Number 2010-168c

2-Nitropropane

Synonyms & Trade Names
Dimethylnitromethane, iso-Nitropropane, 2-NP
CAS No.
79-46-9
RTECS No.
TZ5250000
DOT ID & Guide
2608 129
Formula
(CH3)2CH(NO2)
Conversion
1 ppm = 3.64 mg/m3
IDLH
Ca [100 ppm]
See: 79469
Exposure Limits
NIOSH REL
: Ca See Appendix A
OSHA PEL
†: TWA 25 ppm (90 mg/m3)
Measurement Methods

NIOSH 46
Physical Description
Colorless liquid with a pleasant, fruity odor.
MW:
89.1
BP:
249°F
FRZ:
-135°F
Sol:
2%
VP:
13 mmHg
IP:
10.71 eV
Sp.Gr:
0.99
Fl.P:
75°F
UEL:
11.0%
LEL:
2.6%
Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.
Incompatibilities & Reactivities
Amines; strong acids, alkalis & oxidizers; metal oxides; combustible materials
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin, nose, respiratory system; headache, anorexia, nausea, vomiting, diarrhea; kidney, liver damage; [potential occupational carcinogen]
Target Organs
Eyes, skin, respiratory system, central nervous system, kidneys, liver
Cancer Site
[in animals: liver tumors]
Personal Protection/Sanitation
(See protection codes)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations

NIOSH

At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also: INTRODUCTION   See ICSC CARD: 0187   See MEDICAL TESTS: 0166