September 2010
NIOSH Publication Number 2010-168c

Diisobutyl ketone

Synonyms & Trade Names
DIBK; sym-Diisopropyl acetone; 2,6-Dimethyl-4-heptanone; Isovalerone; Valerone
CAS No.
108-83-8
RTECS No.
MJ5775000
DOT ID & Guide
1157 128
Formula
[(CH3)2CHCH2]2CO
Conversion
1 ppm = 5.82 mg/m3
IDLH
500 ppm
See: 108838
Exposure Limits
NIOSH REL
: TWA 25 ppm (150 mg/m3)
OSHA PEL
†: TWA 50 ppm (290 mg/m3)
Measurement Methods

NIOSH 7
Physical Description
Colorless liquid with a mild, sweet odor.
MW:
142.3
BP:
334°F
FRZ:
-43°F
Sol:
0.05%
VP:
2 mmHg
IP:
9.04 eV
Sp.Gr:
0.81
Fl.P:
120°F		 UEL(200°F): 7.1% LEL(200°F): 0.8%
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
Incompatibilities & Reactivities
Strong oxidizers
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin, nose, throat; headache, dizziness; dermatitis; liver, kidney damage
Target Organs
Eyes, skin, respiratory system, central nervous system, liver, kidneys
Personal Protection/Sanitation
(See protection codes)
Skin: Prevent skin contact
Eyes: No recommendation
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations

NIOSH

Up to 500 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode£
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)£
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also: INTRODUCTION   See ICSC CARD: 0713   See MEDICAL TESTS: 0079