September 2010
NIOSH Publication Number 2010-168c

Cyclohexanone

Synonyms & Trade Names
Anone, Cyclohexyl ketone, Pimelic ketone
CAS No.
108-94-1
RTECS No.
GW1050000
DOT ID & Guide
1915 127
Formula
C6H10O
Conversion
1 ppm = 4.02 mg/m3
IDLH
700 ppm
See: 108941
Exposure Limits
NIOSH REL
: TWA 25 ppm (100 mg/m3) [skin]
OSHA PEL
†: TWA 50 ppm (200 mg/m3)
Measurement Methods

NIOSH 1
Physical Description
Water-white to pale-yellow liquid with a peppermint- or acetone-like odor.
MW:
98.2
BP:
312°F
FRZ:
-49°F
Sol:
15%
VP:
5 mmHg
IP:
9.14 eV
Sp.Gr:
0.95
Fl.P:
111°F
UEL:
9.4%		 LEL(212°F): 1.1%
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
Incompatibilities & Reactivities
Oxidizers, nitric acid
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin, mucous membrane; headache; narcosis, coma; dermatitis; in animals: liver, kidney damage
Target Organs
Eyes, skin, respiratory system, central nervous system, liver, kidneys
Personal Protection/Sanitation
(See protection codes)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations

NIOSH

Up to 625 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode£
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)£

Up to 700 ppm:
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)£
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also: INTRODUCTION   See ICSC CARD: 0425   See MEDICAL TESTS: 0063