3-Pyridinecarboxylic acid
3-Carboxypyridine
Pyridine-beta-carboxylic
Niacin
C6H5NO2/HOOC5H4N
Molecular mass: 123.1
ICSC # 1702
CAS # 59-67-6
RTECS # QT0525000
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/ Fire Fighting
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FIRE
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Combustible.
Gives off irritating or toxic fumes (or gases) in a fire.
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NO open flames.
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Water spray, foam, powder, carbon dioxide
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Explosion
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Finely dispersed particles form explosive mixtures in air.
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Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.
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Exposure
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PREVENT DISPERSION OF DUST!
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Inhalation
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Cough.
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Avoid inhalation of
dust.
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Fresh air, rest.
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Skin
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Protective gloves.
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Rinse skin with plenty of water or shower.
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Eyes
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Redness.
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Safety goggles
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Rinse with plenty of water (remove contact lenses if easily possible).
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Ingestion
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Flushing of the face.
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Give one or two glasses of water to drink.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Personal protection: particulate filter adapted to the airborne concentration of the substance.
Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting.
Carefully collect remainder,
then remove to safe place.
Do NOT let this chemical enter the environment.
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Store in an area without drain or sewer access.
Separated from
strong acids,
bases
and
oxidants
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Signal: Warning
Causes eye irritation
Harmful to aquatic life
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Important Data
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Physical State; Appearance:
WHITE
CRYSTALS
OR
CRYSTALLINE POWDER.
Physical Dangers:
Dust explosion possible if in powder or granular form, mixed with air.
Chemical Dangers:
On combustion, forms
toxic gases,
including
nitrogen oxides.
Reacts
with
oxidants
,
strong acids
and
bases
.
Occupational Exposure Limits:
TLV not established.
MAK not established.
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Routes of Exposure:
Inhalation Risk:
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
Effects of Short-Term Exposure:
The substance
is mildly irritating to
the eyes.
Effects of Long-Term or Repeated Exposure:
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Physical Properties
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Melting point: 236.6°C
Density: 1.5
g/cm3
Solubility in water, g/100 ml at 20°C: 1.8
(moderate)
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Flashpoint: 193°C c.c.
Auto-ignition temperature: 580°C
Explosive limits, vol% in air: 25 - ?
Octanol/water partition coefficient as log Pow: -2.43
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Environmental Data
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The substance is harmful to aquatic organisms.
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N O T E S
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ADDITIONAL INFORMATION
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ICSC: 1702
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NICOTINIC ACID
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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