2,2-Dichloro-1,1-difluoroethyl methyl ether
2,2-Dichloro-1,1-difluoro-1-methoxyethane
Methoflurane
Penthrane
C3H4Cl2F2O / CH3OCF2CHCl2
Molecular mass: 165.0
ICSC # 1636
CAS # 76-38-0
RTECS # KN7820000
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Combustible.
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NO open flames.
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Powder, water spray, foam, carbon dioxide.
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Explosion
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Above 63°C explosive vapour/air mixtures may be formed.
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Above 63°C use a closed system, ventilation.
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Exposure
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•Inhalation
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Dizziness.
Drowsiness.
Unconsciousness.
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Ventilation, local exhaust, or breathing protection.
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Fresh air, rest.
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•Skin
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Protective gloves.
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Rinse skin with plenty of water or shower.
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•Eyes
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Redness.
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Safety spectacles
or eye protection in combination with breathing protection.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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•Ingestion
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Refer for medical attention.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Personal protection: filter respirator for organic gases and vapours.
Collect leaking liquid in sealable metal containers.
Absorb remaining liquid in sand or inert absorbent and remove to safe place.
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Signal: Warning
Health haz
Combustible liquid
May cause damage to kidneys if inhaled
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Important Data
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Physical State; Appearance:
COLOURLESS LIQUID
, WITH CHARACTERISTIC ODOUR.
Physical Dangers:
Chemical Dangers:
The substance decomposes
on burning,
producing
toxic fumes
hydrogen chloride,
hydrogen fluoride
).
Attacks
some forms of
plastic
and
rubber
.
Occupational Exposure Limits:
TLV not established.
MAK not established.
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation of its vapour.
Inhalation Risk:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C.
Effects of Short-Term Exposure:
Exposure at high levels may result in unconsciousness.
Effects of Long-Term or Repeated Exposure:
The substance may have effects on the
kidneys
, resulting in
kidney impairment
.
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Physical
Properties
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Boiling point: 105°C
Melting point: -35°C
Relative density (water = 1): 1.42
Solubility in water, g/100 ml at 37°C: 2.83
(poor)
Vapour pressure, kPa at 20°C: 3.1
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Relative vapour density (air = 1): 5.7
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: 63°C
Explosive limits, vol% in air: 7-?
Octanol/water partition coefficient as log Pow: 2.21
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Environmental
Data
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N O T E S
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ADDITIONAL INFORMATION
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ICSC: 1636
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METHOXYFLURANE
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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