Acetylsalicylic acid
2-Acetoxybenzoic acid
Aspirin
C9H8O4 / CH3COOC6H4COOH
Molecular mass: 180.2
ICSC # 0822
CAS # 50-78-2
RTECS # VO0700000
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/ Fire Fighting
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FIRE
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Combustible.
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NO open flames.
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Powder, water spray, foam, carbon dioxide.
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Explosion
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Finely dispersed particles form explosive mixtures in air.
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Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.
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Exposure
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PREVENT DISPERSION OF DUST!
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Inhalation
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Cough.
Sore throat.
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Ventilation (not if powder).
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Fresh air, rest.
Refer for medical attention.
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Skin
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Redness.
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Protective gloves.
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Rinse skin with plenty of water or shower.
Refer for medical attention.
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Eyes
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Redness.
Pain.
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Safety goggles.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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Ingestion
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Nausea.
Vomiting.
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Refer for medical attention.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting.
Carefully collect remainder,
then remove to safe place.
Personal protection: P2 filter respirator for harmful particles.
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Well closed.
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Important Data
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Physical State; Appearance:
COLOURLESS
TO WHITE
CRYSTALS
OR WHITE CRYSTALLINE POWDER
, WITH CHARACTERISTIC ODOUR.
Physical Dangers:
Dust explosion possible if in powder or granular form, mixed with air.
Chemical Dangers:
The solution in water is a weak acid.
Occupational Exposure Limits:
TLV: 5 mg/m3 (ACGIH 1997).
MAK not established.
OSHA PEL: none
NIOSH REL: TWA 5 mg/m3
NIOSH IDLH: N.D. See: IDLH INDEX
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation and
by ingestion.
Inhalation Risk:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.
Effects of Short-Term Exposure:
The substance
irritates
the eyes,
the skin, and
the respiratory tract.
The substance may cause effects on the blood and central nervous system, if ingested in large amounts.
Effects of Long-Term or Repeated Exposure:
Animal tests show that this substance possibly causes toxic effects upon human reproduction.
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Physical Properties
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Decomposes below boiling point at 140°C
Melting point: 135°C
Density: 1.4
g/cm3
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Solubility in water: poor (0.25 g/100 ml at 15°C)
Vapour pressure, Pa at 25°C: about 0.004
Octanol/water partition coefficient as log Pow: 1.19
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Environmental Data
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N O T E S
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Acenterine, Acesal, Acetol, Acetophen, Acetosal, Acetosalin, Acetylin, Acetylsal, Acisal, Acylpyrin, Asagran, Aspro, Asteric, Caprin, Duramax, Ecotrin, Empirin, Neuronika, Polopiryna, Rhodine, Salacetin, Xaxa are trade names.
Transport Emergency Card: TEC (R)-61G12c
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ADDITIONAL INFORMATION
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ICSC: 0822
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2-(ACETYLOXY)BENZOIC ACID
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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