4-Chloro-o-toluidine
4-Chloro-2-methylaniline
C7H8ClN/ ClC6H3(CH3)NH2
Molecular mass: 141.6
ICSC # 0630
CAS # 95-69-2
RTECS # XU5000000
UN # 2239
EC # 612-196-00-0
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Combustible.
Gives off irritating or toxic fumes (or gases) in a fire.
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NO open flames.
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Water spray,
dry powder,
carbon dioxide.
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Explosion
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Exposure
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AVOID ALL CONTACT!
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IN ALL CASES CONSULT A DOCTOR!
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•Inhalation
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Cough.
Red urine. Frequent, sudden and painful urination.
Abdominal pain.
Blue lips or finger nails.
Blue skin.
Headache.
Dizziness.
Nausea.
Drowsiness.
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Breathing protection.
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Fresh air, rest.
Refer immediately for medical attention.
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•Skin
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Redness.
MAY BE ABSORBED!
(see Inhalation).
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Protective gloves.
Protective clothing.
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Remove contaminated clothes.
Rinse skin with plenty of water or shower.
Refer immediately for medical attention.
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•Eyes
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Redness.
Pain.
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Face shield
or
eye protection in combination with breathing protection if powder.
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Rinse with plenty of water (remove contact lenses if easily possible).
Refer for medical attention.
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•Ingestion
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(see Inhalation).
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Do not eat, drink, or smoke during work.
Wash hands before eating.
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Rinse mouth.
Give one or two glasses of water to drink.
Refer immediately for medical attention.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Personal protection:
chemical protection suit including self-contained breathing apparatus.
Sweep spilled substance into covered container,
then remove to safe place.
Do NOT let this chemical enter the environment.
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Cool.
Separated from
food and feedstuffs.
See Chemical Dangers.
Well closed.
Store in an area without drain or sewer access.
Provision to contain effluent from fire extinguishing.
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Do not transport with food and feedstuffs.
Note: E
T symbol
N symbol
R: 45-23/24/25-68-50/53
S: 53-45-61-60
UN Hazard Class: 6.1
UN Packing Group: III
Signal: Danger
Excl mark-Health haz
Harmful if swallowed
Harmful in contact with skin
May cause genetic defects
May cause cancer
Causes damage to bladder and red blood cells
Harmful to aquatic life
Harmful to aquatic life with long lasting effects
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Important Data
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Physical State; Appearance:
COLOURLESS TO BROWN SOLID IN VARIOUS FORMS
or LIQUID
Physical Dangers:
Chemical Dangers:
The substance decomposes
on burning,
producing
toxic and corrosive fumes
including
hydrogen chloride
and
nitrogen oxides.
Reacts violently with chloroformic acid esters,
strong oxidants,
acid anhydrides,
acids,
acid chlorides.
Occupational Exposure Limits:
TLV not established.
MAK: skin absorption (H);
Carcinogen category: 1; Germ cell mutagen group: 3A
(DFG 2006).
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Routes of Exposure:
The substance can be absorbed into the body through the skin, by inhalation and by ingestion.
Inhalation Risk:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
Effects of Short-Term Exposure:
May cause mechanical irritation to the skin, the respiratory tract. and the eyes (as a solid).
The substance may cause effects on the bladder
, resulting in hemorrhagic inflammation.
The substance may cause effects on the blood
, resulting in the formation of methaemoglobin.
The effects may be delayed.
Medical observation is indicated.
See Notes.
of human intoxications metHb is seen.
Effects of Long-Term or Repeated Exposure:
This substance is probably carcinogenic to humans.
May cause heritable genetic damage to human germ cells.
K 3A and IARC
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Physical
Properties
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Boiling point: 241°C
Melting point: 29-30°C
Density: 1.19
g/cm3
Solubility in water, g/100 ml at 25°C: (very poor) 0.095
Vapour pressure, Pa at 25°C: 5.5
Relative vapour density (air = 1): 4.9
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Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point:
99°C c.c.
Auto-ignition temperature: 560°C
Octanol/water partition coefficient as log Pow: 2.27
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Environmental
Data
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The substance is harmful to aquatic organisms.
It is strongly advised that this substance does not enter the environment.
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N O T E S
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Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Transport Emergency Card: TEC (R)-61GT2-III
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ADDITIONAL INFORMATION
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ICSC: 0630
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2-AMINO-5-CHLOROTOLUENE
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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