Propanoic anhydride
Methylacetic anhydride
Propanoic acid anhydride
C6H10O3 / (CH3CH2CO)2O
Molecular mass: 130.2
ICSC # 0558
CAS # 123-62-6
RTECS # UF9100000
UN # 2496
EC # 607-010-00-X
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Combustible.
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NO open flames.
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Powder, alcohol-resistant foam, water spray, carbon dioxide.
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Explosion
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Above 63°C explosive vapour/air mixtures may be formed.
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Above 63°C use a closed system, ventilation.
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Exposure
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PREVENT GENERATION OF MISTS!
AVOID ALL CONTACT!
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•Inhalation
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Sore throat.
Cough.
Burning sensation.
Shortness of breath.
Symptoms may be delayed (see Notes).
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Ventilation, local exhaust, or breathing protection.
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Fresh air, rest.
Artificial respiration may be needed.
Refer for medical attention.
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•Skin
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Pain.
Blisters.
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Protective gloves.
Protective clothing.
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Remove contaminated clothes.
Rinse skin with plenty of water or shower.
Refer for medical attention.
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•Eyes
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Redness.
Pain.
Severe deep burns.
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Face shield,
or eye protection in combination with breathing protection.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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•Ingestion
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Burning sensation.
Abdominal pain.
Shock or collapse.
Sore throat.
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Do NOT induce vomiting.
Give plenty of water to drink.
Refer for medical attention.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Collect leaking and spilled liquid in sealable containers as far as possible.
Absorb remaining liquid in dry sand or inert absorbent and remove to safe place.
Use face shield.
Chemical protection suit.
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Separated from bases, oxidants and food and feedstuffs.
Dry.
Ventilation along the floor.
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Do not transport with food and feedstuffs.
C symbol
R: 34
S: 1/2-26-45
UN Hazard Class: 8
UN Packing Group: III
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Important Data
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Physical State; Appearance:
COLOURLESS LIQUID
, WITH PUNGENT ODOUR.
Physical Dangers:
The vapour is heavier than air.
Chemical Dangers:
The substance decomposes on contact with water
producing corrosive propionic acid.
Reacts
violently with
bases
and
oxidants
causing fire and explosion hazard.
Occupational Exposure Limits:
TLV not established.
MAK not established.
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation of its aerosol, also as a vapour!
and
by ingestion.
Inhalation Risk:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C.
Effects of Short-Term Exposure:
The substance
is corrosive to
the eyes,
the skin and
the respiratory tract.
Corrosive on ingestion.
Inhalation of vapour or aerosol may cause lung oedema (see Notes).
The effects may be delayed.
Medical observation is indicated.
Effects of Long-Term or Repeated Exposure:
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Physical
Properties
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Boiling point: 167°C
Melting point: -45°C
Relative density (water = 1): 1.01
Solubility in water: reaction
Vapour pressure, kPa at 20°C: . 1
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Relative vapour density (air = 1): 4.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 63°C c.c.
Auto-ignition temperature: 285°C
Explosive limits, vol% in air: 1.3-9.5
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Environmental
Data
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N O T E S
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The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered.
Transport Emergency Card: TEC (R)-80GC3-II+III
NFPA Code: H3; F2; R1;
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ADDITIONAL INFORMATION
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ICSC: 0558
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PROPIONIC ANHYDRIDE
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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