1-Methyl-2-pyrrolidinone
1-Methyl-2-pyrrolidone
N-Methylpyrrolidone
C5H9NO
Molecular mass: 99.1
ICSC # 0513
CAS # 872-50-4
RTECS # UY5790000
EC # 606-021-00-7
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Combustible.
Gives off irritating or toxic fumes (or gases) in a fire.
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NO open flames.
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Powder, alcohol-resistant foam, water spray, carbon dioxide.
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Explosion
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Above 96°C explosive vapour/air mixtures may be formed.
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Above 96°C use a closed system, ventilation.
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Exposure
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PREVENT GENERATION OF MISTS!
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•Inhalation
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Headache.
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Ventilation.
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Fresh air, rest.
Refer for medical attention.
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•Skin
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MAY BE ABSORBED!
Dry skin.
Redness.
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Protective gloves.
Protective clothing.
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Remove contaminated clothes.
Rinse skin with plenty of water or shower.
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•Eyes
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Redness.
Pain.
Blurred vision.
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Safety spectacles.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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•Ingestion
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Do NOT induce vomiting.
Refer for medical attention.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Collect leaking and spilled liquid in sealable containers as far as possible.
Absorb remaining liquid in sand or inert absorbent and remove to safe place.
Personal protection:
filter respirator for organic gases and vapours.
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Separated from
oxidants
,
rubber, plastics, aluminium, light metals.
Dry.
Ventilation along the floor.
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Xi symbol
R: 36/38
S: 2-41
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Important Data
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Physical State; Appearance:
COLOURLESS
HYGROSCOPIC LIQUID
, WITH CHARACTERISTIC ODOUR.
TURNS YELLOW ON Exposure TO HEAT.
Physical Dangers:
Chemical Dangers:
The substance decomposes
on heating
or
on burning
producing
toxic fumes
including
nitrogen oxides
,
carbon monoxide
.
Attacks aluminium, light metals, rubber, plastic.
Occupational Exposure Limits:
TLV not established.
MAK: 20 ppm, 82 mg/m3
Peak limitation category: II(2);
skin absorption (H);
Pregnancy risk group: C;
(DFG 2005).
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation and through the skin.
Inhalation Risk:
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C
; on spraying or dispersing, however, much faster.
Effects of Short-Term Exposure:
The substance
irritates
the eyes
and
the skin.
If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.
Effects of Long-Term or Repeated Exposure:
Repeated or prolonged contact with skin may cause dermatitis.
Animal tests show that this substance possibly causes toxic effects upon human reproduction.
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Physical
Properties
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Boiling point: 202°C
Melting point: -24°C
Relative density (water = 1): 1.03
Solubility in water:
very good
Vapour pressure, Pa at 25°C: 66
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Relative vapour density (air = 1): 3.4
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 96°C o.c.
Auto-ignition temperature: 270°C
Explosive limits, vol% in air: 0.99-3.9
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Environmental
Data
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N O T E S
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N-Methyl-2-pyrrolidone enhances the skin permeability for other substances.
Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
Card has been partly updated in October 2005. See section Occupational Exposure Limits.
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ADDITIONAL INFORMATION
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ICSC: 0513
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N-METHYL-2-PYRROLIDONE
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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