Ethylene glycol monomethyl ether acetate
2-Methoxyethanol acetate
Acetic acid, 2-methoxyethyl ester
Methyl cellosolve acetate
Methyl glycol acetate
C5H10O3 / CH3COOCH2CH2OCH3
Molecular mass: 118.1
ICSC # 0476
CAS # 110-49-6
RTECS # KL5950000
UN # 1189
EC # 607-036-00-1
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Flammable.
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NO open flames, NO sparks, and NO smoking.
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Powder, alcohol-resistant foam, water spray, carbon dioxide.
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Explosion
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Above 45°C explosive vapour/air mixtures may be formed.
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Above 45°C use a closed system, ventilation, and explosion-proof electrical equipment.
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In case of fire: keep drums, etc., cool by spraying with water.
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Exposure
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AVOID ALL CONTACT!
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•Inhalation
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Dizziness.
Drowsiness.
Headache.
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Ventilation, local exhaust, or breathing protection.
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Fresh air, rest.
Refer for medical attention.
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•Skin
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MAY BE ABSORBED!
Dry skin.
(Further see Inhalation).
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Protective gloves.
Protective clothing.
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Remove contaminated clothes.
Rinse skin with plenty of water or shower.
Refer for medical attention.
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•Eyes
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Redness.
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Safety goggles,
or eye protection in combination with breathing protection.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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•Ingestion
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Abdominal pain.
Nausea.
Vomiting.
Weakness.
Unconsciousness.
(Further see Inhalation).
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Do NOT induce vomiting.
Refer for medical attention.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Ventilation.
Remove all ignition sources.
Collect leaking and spilled liquid in sealable containers as far as possible.
Absorb remaining liquid in sand or inert absorbent and remove to safe place.
Do NOT let this chemical enter the environment.
(Extra personal protection: filter respirator for organic gases and vapours.)
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Fireproof.
Separated from
strong oxidants,
strong bases,
strong acids.
Keep in the dark.
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Note: E
T symbol
R: 60-61-20/21/22
S: 53-45
UN Hazard Class: 3
UN Packing Group: III
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Important Data
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Physical State; Appearance:
COLOURLESS LIQUID
, WITH CHARACTERISTIC ODOUR.
Physical Dangers:
Chemical Dangers:
The substance can presumably form explosive peroxides.
Reacts
with
strong oxidants,
strong bases
.
Occupational Exposure Limits:
TLV: 0.1 ppm as TWA; (skin); (ACGIH 2007).
MAK: 5 ppm, 25 mg/m3 H;
Peak limitation category: II(8); Pregnancy risk group: B;
(DFG 2006).
OSHA PEL: TWA 25 ppm (120 mg/m3) skin
NIOSH REL: TWA 0.1 ppm (0.5 mg/m3) skin
NIOSH IDLH: 200 ppm See: 110496
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation of its vapour,
through the skin
and
by ingestion.
Inhalation Risk:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
Effects of Short-Term Exposure:
The vapour
is mildly irritating to
the eyes.
The substance may cause effects on the
bone marrow
and
central nervous system
.
The substance may cause effects on the
blood
, resulting in
lesions of blood cells
and
kidney impairment
at high levels
.
Exposure far above the OEL may result in unconsciousness.
Effects of Long-Term or Repeated Exposure:
The liquid defats the skin.
The substance may have effects on the
bone marrow
and
blood
, resulting in
lesions of blood cells
and
kidney impairment.
May cause toxicity to human reproduction or development.
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Physical
Properties
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Boiling point: 145°C
Melting point: -65°C
Relative density (water = 1): 1.01
Solubility in water:
miscible
Vapour pressure, kPa at 20°C: 0.27
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Relative vapour density (air = 1): 4.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 45°C c.c.
Auto-ignition temperature: 380°C
Explosive limits, vol% in air: 1.5 (93°C) - 12.3 (93°C)
Octanol/water partition coefficient as log Pow: 0.121
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Environmental
Data
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The substance is harmful to aquatic organisms.
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N O T E S
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Check for peroxides prior to distillation; eliminate if found.
Health effects of exposure to the substance have not been investigated adequately.
Its effects are deduced from those of similar substances.
Transport Emergency Card: TEC (R)-30GF1-III
NFPA Code: H1; F2; R
Card has been partially updated in July 2007: see Occupational Exposure Limits.
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ADDITIONAL INFORMATION
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ICSC: 0476
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2-METHOXYETHYL ACETATE
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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