O-3-Chloro-4-methyl-2-oxo-2H-chromen-7-yl O,O-diethyl phosphorothioate
Phosphorothioic acid O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl ester
O,O-Diethyl O-(3-chloro-4-methyl-7-coumarinyl)phosphorothioate
O,O-Diethyl 3-chloro-4-methyl-7-umbelliferone thiophosphate
C14H16ClO5PS
Molecular mass: 362.78
ICSC # 0422
CAS # 56-72-4
RTECS # GN6300000
UN # 3027
EC # 015-038-00-3
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Not combustible.
Liquid formulations containing organic solvents may be flammable.
Gives off irritating or toxic fumes (or gases) in a fire.
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In case of fire in the surroundings: powder, water spray, foam, carbon dioxide.
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Explosion
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Exposure
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PREVENT DISPERSION OF DUST!
STRICT HYGIENE!
AVOID Exposure OF ADOLESCENTS AND CHILDREN!
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IN ALL CASES CONSULT A DOCTOR!
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•Inhalation
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Convulsions.
Dizziness.
Sweating.
Laboured breathing.
Nausea.
Unconsciousness.
Pupillary constriction, muscle cramp, excessive salivation.
Symptoms may be delayed (see Notes).
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Local exhaust or breathing protection.
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Fresh air, rest.
Artificial respiration may be needed.
Refer for medical attention.
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•Skin
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MAY BE ABSORBED!
(Further see Inhalation).
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Protective gloves.
Protective clothing.
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Remove contaminated clothes.
Rinse skin with plenty of water or shower.
Refer for medical attention.
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•Eyes
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Face shield
or
eye protection in combination with breathing protection.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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•Ingestion
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Abdominal cramps.
Diarrhoea.
Vomiting.
(Further see Inhalation).
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Induce vomiting (ONLY IN CONSCIOUS PERSONS!).
Rest.
Refer for medical attention.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Personal protection: complete protective clothing including self-contained breathing apparatus.
Evacuate danger area!
Do NOT wash away into sewer.
Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting.
Carefully collect remainder,
then remove to safe place.
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Separated from
food and feedstuffs
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Well closed.
Keep in a well-ventilated room.
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Do not transport with food and feedstuffs.
Severe
marine pollutant.
T+ symbol
N symbol
R: 21-28-50/53
S: 1/2-28-36/37-45-60-61
UN Hazard Class: 6.1
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Important Data
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Physical State; Appearance:
COLOURLESS
CRYSTALS
, WITH CHARACTERISTIC ODOUR.
Physical Dangers:
Chemical Dangers:
The substance decomposes
on heating
producing
toxic fumes
including
sulfur oxides
,
phosphorus oxides
and
hydrogen chloride
.
Reacts slowly with bases to be hydrolyzed.
Occupational Exposure Limits:
TLV: 0.05 mg/m3
(inhalable fraction & vapour)
as TWA (skin) A4 (not classifiable as a human carcinogen); BEI issued (ACGIH 2007).
MAK not established.
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation of its aerosol,
through the skin
and
by ingestion.
Inhalation Risk:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.
Effects of Short-Term Exposure:
Cholinesterase inhibitor.
The effects may be delayed.
Medical observation is indicated.
Effects of Long-Term or Repeated Exposure:
Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.
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Physical
Properties
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Melting point: 91°C
Density: 1.47
g/cm3
Solubility in water:
none
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Vapour pressure, Pa at 20°C: 0.000013
Octanol/water partition coefficient as log Pow: 4.13
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Environmental
Data
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The substance is very toxic to aquatic organisms.
This substance may be hazardous to the environment; special attention should be given to fish, crustacea, birds and mammals.
Bioaccumulation of this chemical may occur in fish.
This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal.
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N O T E S
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Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Asuntol, Co-ral, Meldane, Muscatox, Perizin, Resitox, Negashunt are trade names.
Card has been partly updated in October 2005. See section Emergency Response.
Transport Emergency Card: TEC (R)-61GT7-I
Card has been partially updated in July 2007: see Occupational Exposure Limits.
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ADDITIONAL INFORMATION
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ICSC: 0422
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COUMAPHOS
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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