4-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)
2,6-Piperidinedione
C15H23NO4
Molecular mass: 281.35
ICSC # 0244
CAS # 66-81-9
RTECS # MA4375000
UN # 2588
EC # 613-140-00-8
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Gives off irritating or toxic fumes (or gases) in a fire.
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In case of fire in the surroundings: use appropriate extinguishing media.
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Explosion
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Exposure
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PREVENT DISPERSION OF DUST!
STRICT HYGIENE!
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•Inhalation
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Local exhaust or breathing protection.
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Fresh air, rest.
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•Skin
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Redness.
Pain.
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Protective gloves.
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Remove contaminated clothes.
Rinse and then wash skin with water and soap.
Refer for medical attention.
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•Eyes
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Redness.
Pain.
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Safety spectacles.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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•Ingestion
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Diarrhoea.
Unconsciousness.
See Notes.
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Induce vomiting (ONLY IN CONSCIOUS PERSONS!).
Rest.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Evacuate danger area!
Consult an expert!
Do NOT wash away into sewer.
Sweep spilled substance into sealable containers.
Carefully collect remainder,
then remove to safe place.
Personal protection: P2 filter respirator for harmful particles.
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Separated from
food and feedstuffs
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Well closed.
Keep in a well-ventilated room.
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Unbreakable packaging; put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs.
T+ symbol
N symbol
R: 61-28-51/53-68
S: 53-45-61
UN Hazard Class: 6.1
UN Packing Group: I
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Important Data
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Physical State; Appearance:
COLOURLESS
CRYSTALS.
Physical Dangers:
Chemical Dangers:
The substance decomposes
on heating
producing
toxic and corrosive fumes
including
nitrogen oxides
.
Occupational Exposure Limits:
TLV not established.
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation
and
by ingestion.
Inhalation Risk:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.
Effects of Short-Term Exposure:
The substance
irritates
the eyes
and
the skin.
Exposure may result in death.
See Notes.
Effects of Long-Term or Repeated Exposure:
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Physical
Properties
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Melting point: 119.5-121°C
Solubility in water, g/100 ml at 2°C: 2.1
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Octanol/water partition coefficient as log Pow: 0.55
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Environmental
Data
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This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal.
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N O T E S
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Depending on the degree of exposure, periodic medical examination is suggested.
Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
Animal studies have indicated that the substance may be very toxic by ingestion.
Hizarocin, Acti-dione, Acti-aid, Naramycin, Naramycin A and Neocycloheximide are trade names.
Card has been partly updated in October 2005. See sections EU classification, Emergency Response.
Transport Emergency Card: TEC (R)-61GT7-I
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ADDITIONAL INFORMATION
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ICSC: 0244
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CYCLOHEXIMIDE
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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