ACETIC ANHYDRIDE ICSC: 0209 Acetic acid, anhydride Acetic oxide Ethanoic anhydride Acetyl oxide C4H6O3/(CH3CO)2O Molecular mass: 102.1 ICSC #    0209 CAS #     108-24-7 RTECS # AK1925000 UN #        1715 EC #         607-008-00-9 Types of Hazard/ Exposure Acute Hazards/ Symptoms Prevention First Aid/ Fire Fighting FIRE Flammable. NO open flames, NO sparks, and NO smoking. Alcohol-resistant foam, powder, carbon dioxide (see Notes). Explosion Above 49°C explosive vapour/air mixtures may be formed. Above 49°C use a closed system, ventilation, and explosion-proof electrical equipment. In case of fire: cool drums, etc., by spraying with water but avoid contact of the substance with water. Exposure AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!  •Inhalation Cough. Laboured breathing. Shortness of breath. Sore throat. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •Skin Redness. skin burns. Pain. Blisters. Effects could be delayed Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.  •Eyes Causes watering of the eyes. Redness. Pain. Burns. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •Ingestion Abdominal pain. Burning sensation. Shock or collapse. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention. Spillage Disposal Storage Packaging & Labelling Personal protection: filter respirator for acid gases. Chemical protection suit. Use face shield. Consult an expert! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Fireproof. Separated from food and feedstuffs, incompatible substances (see Chemical Dangers). Dry. Do not transport with food and feedstuffs. C symbol R: 10-20/22-34 S: 1/2-26-36/37/39-45 UN Hazard Class: 8 UN Subsidiary Risks: 3 UN Packing Group: II Signal: Danger Flame-Corr-Excl mark Flammable liquid and vapour Harmful if swallowed Causes severe skin burns and eye damage Causes serious eye damage ACETIC ANHYDRIDE ICSC: 0209 Important Data Physical State; Appearance: COLOURLESS LIQUID , WITH PUNGENT ODOUR. Physical Dangers: Chemical Dangers: The substance decomposes on burning producing toxic gases and toxic fumes including acetic acid fumes . Reacts violently with alcohols, amines, oxidants, strong bases and water. Attacks many metals in presence of water or when dry. Occupational Exposure Limits: TLV: 5 ppm as TWA (ACGIH 2006). MAK: 5 ppm 21 mg/m3 Peak limitation category: I (I) Pregnancy risk group: D (DFG 2006). OSHA PEL: TWA 5 ppm (20 mg/m3) NIOSH REL: C 5 ppm (20 mg/m3) NIOSH IDLH: 200 ppm See: 108247 Routes of Exposure: The substance can be absorbed into the body by inhalation of its vapour and by ingestion . Inhalation Risk: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. Effects of Short-Term Exposure: Tear drawing. The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of the substance may cause asthma-like reactions. Effects of Long-Term or Repeated Exposure: Inhalation of the substance may cause asthma-like reactions (RADS). Physical Properties Boiling point: 139°C Melting point: -73°C Relative density (water = 1): 1.08 Solubility in water: Reaction Vapour pressure, kPa at 20°C: 0.5 Relative vapour density (air = 1): 3.5 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01 Flash point: 49°C c.c. Auto-ignition temperature: 316°C Explosive limits, vol% in air: 2.7-10.3 Octanol/water partition coefficient as log Pow: -0.27 Environmental Data N O T E S Forms acetic acid when mixed with water. Major fires must be extinguished with large amounts of water from a distance. Transport Emergency Card: TEC (R)-80S1715 NFPA Code: H 2; F 2; R 1; W Card has been partially updated in July 2007: see Occupational Exposure Limits. ADDITIONAL INFORMATION ICSC: 0209 ACETIC ANHYDRIDE (C) IPCS, CEC, 1994 IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.