1,2-Epoxy-3-isopropoxypropane
IGE
(Isopropoxymethyl)oxirane
C6H12O2
Molecular mass: 116.2
ICSC # 0171
CAS # 4016-14-2
RTECS # TZ3500000
UN # 1993
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Flammable.
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NO open flames, NO sparks, and NO smoking.
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Powder, AFFF, foam, carbon dioxide.
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Explosion
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Above 33°C explosive vapour/air mixtures may be formed.
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Above 33°C use a closed system, ventilation, and explosion-proof electrical equipment.
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In case of fire: keep drums, etc., cool by spraying with water.
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Exposure
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PREVENT GENERATION OF MISTS!
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•Inhalation
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Burning sensation.
Cough.
Dizziness.
Headache.
Laboured breathing.
Shortness of breath.
Sore throat.
Symptoms may be delayed (see Notes).
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Ventilation, local exhaust, or breathing protection.
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Fresh air, rest.
Half-upright position.
Refer for medical attention.
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•Skin
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Redness.
Pain.
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Protective gloves.
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Remove contaminated clothes.
Rinse and then wash skin with water and soap.
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•Eyes
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Redness.
Pain.
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Safety spectacles
or
eye protection in combination with breathing protection.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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•Ingestion
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Give plenty of water to drink.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Collect leaking and spilled liquid in sealable containers as far as possible.
Carefully collect remainder,
then remove to safe place.
Personal protection:
filter respirator for organic gases and vapours.
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Fireproof.
Separated from
strong oxidants,
acids.
Cool.
Dry.
Keep in the dark.
Well closed.
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UN Hazard Class: 3
UN Packing Group: III
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Important Data
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Physical State; Appearance:
COLOURLESS LIQUID
Physical Dangers:
Chemical Dangers:
The substance can presumably form explosive peroxides upon exposure to air or light.
Reacts
violently with
strong oxidants
amines
and
acids
.
Occupational Exposure Limits:
TLV: 50 ppm as TWA, 75 ppm as STEL; (ACGIH 2004).
MAK:
Carcinogen category: 3B;
(DFG 2004).
OSHA PEL: TWA 50 ppm (240 mg/m3)
NIOSH REL: C 50 ppm (240 mg/m3) 15-minute
NIOSH IDLH: 400 ppm See: 4016142
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation of its vapour.
Inhalation Risk:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
Effects of Short-Term Exposure:
The substance
is irritating to
the eyes
,
the skin
and
the respiratory tract
.
Inhalation of vapour may cause lung oedema (see Notes).
The substance may cause effects on the central nervous system.
Exposure above the OEL could cause lowering of consciousness.
Effects of Long-Term or Repeated Exposure:
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Physical
Properties
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Boiling point: 137°C
Relative density (water = 1): 0.92
Solubility in water, g/100 ml: 19
Vapour pressure, kPa at 25°C: 1.25
Relative vapour density (air = 1): 4.15
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Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04
Flash point: 33°C c.c.
Explosive limits, vol% in air: see Notes
Octanol/water partition coefficient as log Pow: 0.5
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Environmental
Data
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N O T E S
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Explosive limits are unknown in literature, although the substance is combustible and has a flash point < 61°C.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
Check for peroxides prior to distillation; eliminate if found.
Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response.
Transport Emergency Card: TEC (R)-30GF1-III
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ADDITIONAL INFORMATION
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ICSC: 0171
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ISOPROPYL GLYCIDYL ETHER
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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