1,1,3-Trimethyl-3-cyclohexene-5-one
3,5,5-Trimethylcyclohex-2-enone
Isoacetophorone
C9H14O
Molecular mass: 138.2
ICSC # 0169
CAS # 78-59-1
RTECS # GW7700000
EC # 606-012-00-8
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Types of Hazard/ Exposure
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Acute Hazards/ Symptoms
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Prevention
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First Aid/
Fire Fighting
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FIRE
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Combustible.
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NO open flames.
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Powder, water spray, foam, carbon dioxide.
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Explosion
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Above 84°C explosive vapour/air mixtures may be formed.
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Above 84°C use a closed system, ventilation.
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Exposure
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PREVENT GENERATION OF MISTS!
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•Inhalation
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Burning sensation.
Sore throat.
Cough.
Dizziness.
Headache.
Nausea.
Shortness of breath.
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Ventilation, local exhaust, or breathing protection.
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Fresh air, rest.
Artificial respiration may be needed.
Refer for medical attention.
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•Skin
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Protective gloves.
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Remove contaminated clothes.
Rinse and then wash skin with water and soap.
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•Eyes
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Redness.
Pain.
Blurred vision.
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Safety spectacles.
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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•Ingestion
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Abdominal pain.
(Further see Inhalation).
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Do not eat, drink, or smoke during work.
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Rinse mouth.
Give a slurry of activated charcoal in water to drink.
Do NOT induce vomiting.
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Spillage Disposal
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Storage
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Packaging & Labelling
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Collect leaking and spilled liquid in sealable containers as far as possible.
Absorb remaining liquid in sand or inert absorbent and remove to safe place.
Personal protection:
filter respirator for organic gases and vapours.
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Separated from
strong oxidants,
strong bases,
amines
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Xn symbol
R: 21/22-36/37-40
S: 2-13-23-36/37/39-46
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Important Data
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Physical State; Appearance:
COLOURLESS LIQUID
, WITH CHARACTERISTIC ODOUR.
Physical Dangers:
Chemical Dangers:
Reacts
with
strong oxidants,
strong bases
and
amines.
Occupational Exposure Limits:
TLV: 5 ppm; (Ceiling value); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004).
MAK: 2 ppm, 11 mg/m3
Peak limitation category: I(2); Carcinogen category: 3B; Pregnancy risk group: C;
(DFG 2004).
OSHA PEL: TWA 25 ppm (140 mg/m3)
NIOSH REL: TWA 4 ppm (23 mg/m3)
NIOSH IDLH: 200 ppm See: 78591
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Routes of Exposure:
The substance can be absorbed into the body
by inhalation,
through the skin
and
by ingestion.
Inhalation Risk:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.
Effects of Short-Term Exposure:
The substance
and
the vapour of this substance
is irritating to
the eyes
and
the respiratory tract
.
The substance may cause effects on the
central nervous system
.
Effects of Long-Term or Repeated Exposure:
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Physical
Properties
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Boiling point: 215°C
Melting point: -8°C
Relative density (water = 1): 0.92
Solubility in water, g/100 ml at 25°C: 1.2
Vapour pressure, Pa at 20°C: 40
Relative vapour density (air = 1): 4.8
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Flash point:
84°C c.c.
Auto-ignition temperature: 460°C
Explosive limits, vol% in air: 0.8-3.8
Octanol/water partition coefficient as log Pow: 1.67
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Environmental
Data
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N O T E S
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The occupational exposure limit value should not be exceeded during any part of the working exposure.
Card has been partly updated in April 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
NFPA Code: H 2; F 2; R 0;
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ADDITIONAL INFORMATION
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ICSC: 0169
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ISOPHORONE
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(C) IPCS, CEC, 1994
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IMPORTANT LEGAL NOTICE:
Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH,
the CEC or the IPCS is responsible for the use which might be made of this
information. This card contains the collective views of the IPCS Peer Review Committee and may
not reflect in all cases all the detailed requirements included in national legislation
on the subject. The user should verify compliance of the cards with the relevant legislation
in the country of use.
The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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